Liu Laboratory
ABOUT THE LAB
Programmable Genome Engineering for Genetic Disease Therapy
The Liu Lab develops next-generation genome editing technologies and investigates DNA repair mechanisms to enable precise and efficient genome engineering. Our research combines innovative editing strategies with advanced delivery approaches to expand the therapeutic potential of genome editing for genetic diseases.





Featured Publications
Explore some of the lab's featured publications below. For a complete list, visit the Publications page.
Nature
ARTICLE · 2026
Liu B*, Petti A, Zhou X, Cheng H, Gao J, Yee M, Qiao Y, Zhang Y, Zhou L, Wolfe SA, Jiang T, Sontheimer EJ*, Xue W*
Nature Biotechnology
ARTICLE · 2024
Liu B, Dong X, Zheng C, Keener D, Chen Z, Cheng H, Watts JK, Xue W*, Sontheimer EJ*
Nature Biotechnology
ARTICLE · 2022
Liu B, Dong X, Cheng H, Zheng C, Chen Z, Rodríguez TC, Liang SQ, Xue W*, Sontheimer EJ*
Nature Communications
ARTICLE · 2023
Zheng C+, Liu B+, Dong X, Gaston N, Sontheimer EJ, Xue W*
Nucleic Acids Research
ARTICLE · 2020
Liu B*, Chen S, La Rose A, Chen D, Cao F, Zwinderman M, Kiemel D, Aïssi M, Dekker FJ, Haisma HJ*